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ASSOCIATION OF SERUM COPEPTIN, CARDIAC TROPONIN T, AND ADIPONECTIN WITH ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE: A HOSPITAL-BASED CASE-CONTROL STUDY

Joshi, Prangyada Reecha, Samal, Pradosh, Swain, Banashree · International Journal of Clinical and Biomedical Research;

Background: Copeptin reflects activation of the arginine vasopressin stress axis, cardiac troponin T indicates myocardial injury, and adiponectin has anti-inflammatory and anti-atherogenic properties. Their combined rel…

EFFECTIVENESS OF A STRUCTURED COPING INTERVENTION ON CAREGIVER BURDEN AND COPING STRATEGIES AMONG CAREGIVERS OF HOME-BASED PALLIATIVE CANCER PATIENTS: A QUASI-EXPERIMENTAL STUDY

Gaikwad Priyanka A, Chandekar Pratibha A · International Journal of Clinical and Biomedical Research;

Background: Family caregivers are central to the delivery of home-based palliative care for patients with advanced cancer, yet many experience substantial physical, emotional, social, and financial strain. Structured co…

ULTRASONOGRAPHIC STUDY OF MORPHOGENESIS OF THE FETAL CLAVICLE AND ESTIMATION OF GESTATIONAL AGE

Keshari Kumar Tiwari, Arjun Singh Parmar, Amaresh Kumar Shukla, Chandraprabha Choudhary, Meghana Mishra, Richa Singh, Bhaskar Reddy · International Journal of Clinical and Biomedical Research;

Accurate estimation of gestational age (GA) is central to antenatal care because it informs fetal growth assessment, timing of obstetric interventions, counselling, and perinatal risk stratification. Although convention…

MORPHOMETRIC ANALYSIS OF CERVICAL VERTEBRAL PEDICLES AND UNCINATE PROCESSES: CLINICAL IMPLICATIONS IN AN OSTEOLOGICAL SAMPLE FROM THE VINDHYA REGION

Ashish Tiwari, Bhaskar Reddy, Chandraprabha Choudhary, Meghana Mishra, Arjun Singh Parmar · International Journal of Clinical and Biomedical Research;

The cervical vertebrae support the skull, permit complex neck movements and protect the spinal cord and vertebral vessels. Precise morphometric knowledge of the cervical pedicle and uncinate process is essential for saf…

TEMPORAL LOBE ASYMMETRY: A MORPHOMETRIC ANALYSIS

Suchitra Somkuwar, Rajesh R Vijay Kumar, M. Rajneesh · International Journal of Clinical and Biomedical Research;

Objective: An attempt was done to find out asymmetry of temporal lobe to advocate further consideration of "heschl gyrus and planum temporale in investigations of an anatomic basis for language or auditory functional as…

ASSOCIATION OF CHEST TRAUMA WITH CLINICAL OUTCOMES IN PATIENTS WITH TRAUMATIC BRAIN INJURY: A PROSPECTIVE OBSERVATIONAL STUDY IN A TERTIARY CARE MEDICAL CENTRE

Kapil Dhiman, Gaurav Bajpai, Naveen Kumar Patbamniya, Anuj Pratap Singh, Sudhir Singh Pal, Sandeep Jain, Pragyey Nawlakhe · International Journal of Clinical and Biomedical Research;

Background: Traumatic brain injury (TBI) is a major cause of morbidity and mortality worldwide. Associated chest trauma is frequently encountered in patients with TBI and may adversely affect neurological recovery by ca…

CORRELATION BETWEEN CLINICAL, RADIOLOGICAL, AND INTRAOPERATIVE FINDINGS IN ACUTE APPENDICITIS: A PROSPECTIVE OBSERVATIONAL STUDY

Jaya Sakthi S, Narendar, Kavin Shivan · International Journal of Clinical and Biomedical Research;

Acute appendicitis is a common surgical emergency whose diagnosis, although fundamentally clinical, is frequently supplemented by imaging. The Modified Alvarado (MANTRELS) score offers a structured, stepwise means of es…

APACHE II, APACHE III AND SOFA SCORES AS PREDICTORS OF MORTALITY IN ACUTE RESPIRATORY DISTRESS SYNDROME: A COMPARATIVE PROSPECTIVE STUDY WITH ROC ANALYSIS

Hakim Baset, K, Harika, Mithun N. Kagalkar · International Journal of Clinical and Biomedical Research;

Background: APACHE II, APACHE III and SOFA are widely used intensive care severity scores, but their comparative discrimination for mortality in acute respiratory distress syndrome (ARDS) is not well established in Indi…

ALTERATION OF COAGULATION PROFILE AS A PREDICTOR OF BLEEDING AND MORTALITY IN PATIENTS WITH LEPTOSPIROSIS: A PROSPECTIVE OBSERVATIONAL STUDY

Mithun N. Kagalkar, Harika K, Hakim Baset · International Journal of Clinical and Biomedical Research;

Background: Bleeding is a recognised complication of severe leptospirosis, but data correlating coagulation parameters with bleeding and outcome remain limited from Indian centres. Methods: In this prospective, single-c…

AETIOLOGY, CLINICAL PROFILE AND DEMOGRAPHIC DETERMINANTS OF SEVERITY AND OUTCOME IN ACUTE RESPIRATORY DISTRESS SYNDROME: A PROSPECTIVE OBSERVATIONAL STUDY FROM A MEDICAL ICU

Hakim Baset, Mithun N. Kagalkar, K, Harika · International Journal of Clinical and Biomedical Research;

Background: Acute respiratory distress syndrome (ARDS) has diverse aetiologies and a variable course. Indian intensive care unit (ICU) data on how demographic factors, mode of admission and aetiology relate to Berlin se…

COMORBIDITIES AND ADDICTIONS AS PREDICTORS OF SEVERITY AND OUTCOME IN ACUTE RESPIRATORY DISTRESS SYNDROME: A PROSPECTIVE OBSERVATIONAL STUDY

Hakim Baset, Mithun N. Kagalkar, K, Harika · International Journal of Clinical and Biomedical Research;

Background: Pre-existing comorbidities and addictions are common in critically ill patients, but their contribution to severity and mortality once acute respiratory distress syndrome (ARDS) is established is incompletel…

CLINICAL, HAEMATOLOGICAL, BIOCHEMICAL AND ARTERIAL BLOOD GAS PARAMETERS AS PREDICTORS OF SEVERITY AND OUTCOME IN ACUTE RESPIRATORY DISTRESS SYNDROME

Hakim Baset, Mithun N. Kagalkar, K, Harika · International Journal of Clinical and Biomedical Research;

Background: Bedside vital signs and routine laboratory tests are available within minutes of intensive care unit (ICU) admission, but their comparative value in tracking severity and mortality in acute respiratory distr…

INTERVENTIONS, COMPLICATIONS AND ICU COURSE AS PREDICTORS OF OUTCOME IN ACUTE RESPIRATORY DISTRESS SYNDROME: A PROSPECTIVE OBSERVATIONAL STUDY

Hakim Baset, K, Harika, Mithun N. Kagalkar · International Journal of Clinical and Biomedical Research;

Background: Patients with acute respiratory distress syndrome (ARDS) frequently require organ support and develop intensive care unit (ICU)-acquired complications. How these relate to severity and mortality is less well…

CLINICO-EPIDEMIOLOGICAL PROFILE, COMORBIDITIES AND CO-INFECTIONS AS DETERMINANTS OF OUTCOME IN LEPTOSPIROSIS: A PROSPECTIVE OBSERVATIONAL STUDY

Mithun N. Kagalkar, Arvind M N, K, Harika · International Journal of Clinical and Biomedical Research;

Background: Leptospirosis is an underreported zoonosis with a broad clinical spectrum. Indian data on how comorbidity and co-infection relate to outcome remain limited. Methods: In this prospective, single-centre observ…

ORGAN-SYSTEM COMPLICATIONS AND THEIR ASSOCIATION WITH MORTALITY IN SEVERE LEPTOSPIROSIS: A PROSPECTIVE OBSERVATIONAL STUDY

K, Harika, Mithun N. Kagalkar, Radha A · International Journal of Clinical and Biomedical Research;

Background: Severe leptospirosis involves multiple organ systems, and the relative contribution of each to mortality is not well quantified in Indian cohorts. Methods: In this prospective, single-centre observational st…

WEIL'S SYNDROME AND CLINICAL OUTCOME IN LEPTOSPIROSIS: A PROSPECTIVE OBSERVATIONAL STUDY

Mithun N. Kagalkar, K, Harika, Radha A · International Journal of Clinical and Biomedical Research;

Background: Weil's syndrome - the combination of jaundice, renal dysfunction and haemorrhagic diathesis - represents the most severe phenotype of leptospirosis, but its incidence and outcome relative to non-icteric dise…

INITIAL SYMPTOMATOLOGY AS A PREDICTOR OF CLINICAL OUTCOME IN LEPTOSPIROSIS: A PROSPECTIVE OBSERVATIONAL STUDY

K, Harika, Radha A, Mithun N. Kagalkar · International Journal of Clinical and Biomedical Research;

Background: Leptospirosis presents with a wide, non-specific symptom spectrum that delays diagnosis. Identifying which presenting features carry prognostic weight could support earlier triage. Methods: In this prospecti…

CLONIDINE VERSUS DEXAMETHASONE AS AN ADJUVANT TO 0.25% BUPIVACAINE FOR WOUND INFILTRATION ANALGESIA AFTER ELECTIVE CAESAREAN SECTION

Geetha M, Lokesh S B, Sumanth S, Balaji Nallathambi · International Journal of Clinical and Biomedical Research;

Background: Pain after caesarean section interferes with early ambulation, maternal comfort and the establishment of breastfeeding. Wound infiltration with local anaesthetic is a simple, inexpensive adjunct to multimoda…

COMPARATIVE HISTOLOGICAL STUDY ON THE SPLEEN OF HUMAN, GOAT, DOG, RABBIT AND PIG

Ashwin Kumar, Bhaskar B. Reddy, Chandraprabha Choudhary, Meghana Mishra, Arjun Singh Parmar · International Journal of Clinical and Biomedical Research;

Background: The spleen is the largest secondary lymphoid organ and contributes to immune defence, blood filtration, clearance of senescent erythrocytes, iron recycling, and haematological regulation. Its microarchitectu…

PATIENT PREFERENCES AND UTILIZATION PATTERNS FOR GENERIC VERSUS BRANDED MEDICINES: AN OBSERVATIONAL CROSS-SECTIONAL ANALYSIS

Lagishetty Radhakrishna, Shaik Muddasirun, K. V. R. Barath Raju · International Journal of Clinical and Biomedical Research;

Generic medicines are central to containing healthcare costs and improving access to essential treatment. Despite sustainedgovernment initiatives promoting their use in India, the acceptance and utilization of generic m…

REDUCED SERUM AND URINARY FLUORIDE IN DIABETIC NEPHROPATHY: RELATIONSHIP WITH RENAL DYSFUNCTION AND OXIDATIVE STRESS IN TYPE 2 DIABETES MELLITUS

Yadav, Bhuneshwar, Joshi , Prangyada Reecha, Verma, Kshitij, K N, Shashidhar · International Journal of Clinical and Biomedical Research;

Background: Type 2 Diabetes Mellitus (T2DM) is a major cause of diabetic nephropathy (DN) and progressive renal dysfunction. Impaired kidney function may result in fluoride retention, which, together with hyperglycemia-…

INTEGRATIVE ASSESSMENT OF PHENOTYPIC AND MOLECULAR APPROACHES FOR EVALUATING BIOFILM FORMATION IN CLINICAL ISOLATES OF COAGULASE-NEGATIVE STAPHYLOCOCCI

Vanaparthi, Nagarajuu, Sadawarte, Kalpana · International Journal of Clinical and Biomedical Research;

Several bacterial species once dismissed as harmless commensals are increasingly implicated in human infection. Coagulase-negative staphylococci (CoNS) are a prominent example, causing a broad spectrum of disease in hos…

POSTOPERATIVE WOUND INFECTIONS WITH SPECIAL REFERENCE TO METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS: A THREE-YEAR EXPERIENCE AT MULTICENTRE TERTIARY CARE TEACHING HOSPITALS IN SOUTH INDIA

Vanaparthi, Nagarajuu, Mudu, Venkateswarlu, P, Vimala · International Journal of Clinical and Biomedical Research;

Infections are among the most common adverse events affecting patient safety. Among the various healthcare-associated infections (HAI), surgical site infection (SSI) is a serious postoperative complication occurring in…

HAND GRIP STRENGTH IN RELATION TO THE SIX-MINUTE WALK TEST AMONG PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

S, Praveen Kumar, B, Jayaprakash · International Journal of Clinical and Biomedical Research;

Chronic obstructive pulmonary disease (COPD) is characterised by progressive airflow limitation, diminished exercise tolerance, and skeletal muscle dysfunction. Objective assessment of functional exercise capacity is ce…

COMPARATIVE EVALUATION OF PERIPHERAL BLOOD SMEAR AND IMMUNOCHROMATOGRAPHIC TEST FOR MALARIA DIAGNOSIS IN A RURAL TERTIARY CARE HOSPITAL

Patel, Anishka, R, Sinha, SB, Roushani, DS, Bhalerao, Vaidya, SM, Jain · International Journal of Clinical and Biomedical Research;

Background: Malaria remains a major public health concern in India, particularly in rural settings, where accurate and rapid diagnosis is crucial for effective management. Although peripheral blood smear (PBS) examinati…