Scholarly Article
CLINICORADIOLOGICAL AND HISTOPATHOLOGICAL SPECTRUM OF ECTOPIC PREGNANCY AT TUBAL AND UNUSUAL IMPLANTATION SITES: A TWO-YEAR RETROSPECTIVE CASE ANALYSIS
Mohanty, Suravi, Giri, Ranjana, Macwan, Pankti, Pradhan, Prita
2026-07-26 · International Journal of Clinical and Biomedical Research · Sumathi Publications
Abstract
Background: Ectopic pregnancy is implantation of a fertilized ovum outside the endometrial cavity and remains an important cause of first-trimester maternal morbidity. Although most ectopic pregnancies are tubal, implantation may occur in the ovary, a previous caesarean scar, the cervix, myometrium, or peritoneal cavity. These uncommon sites may mimic adnexal or pelvic masses and can be difficult to diagnose clinically and radiologically. Methods: This retrospective case series included 27 histopathological confirmed ectopic pregnancies diagnosed between January 2023 and January 2025 at a tertiary care teaching hospital. Demographic, obstetric, clinical, and radiological data were retrieved from records. Surgical specimens were fixed in 10% neutral buffered formalin, processed routinely, and examined on hematoxylin and eosinstained sections. Particular attention was given to unusual implantation sites and cases with clinic-radiological diagnostic difficulty. Results: The mean age was 32.37 ± 4.25 years, and the mean estimated gestational age was 43.08 ± 16.80 days. Abdominal pain was the predominant presentation. Twenty-three cases (85.2%) were tubal, three (11.1%) were ovarian, and one (3.7%) involved a previous caesarean scar. Thirteen tubal pregnancies were left-sided and ten were right-sided. Histological examination demonstrated chorionic villi, trophoblastic tissue, decidualized stroma, fibrin, and hemorrhage in the relevant anatomical site. Several cases had been radiologically interpreted as tubo-ovarian or adnexal masses, hemorrhagic ovarian cyst, or pelvic collection before histopathological confirmation. Conclusion: Ectopic pregnancy may present at unusual implantation sites and may mimic non-gestational adnexal or pelvic lesions. Integration of clinical history, serum or urine pregnancy testing, high-quality imaging, operative findings, and histopathology is essential for accurate diagnosis and timely management.
Keywords
Ectopic
Citation Details
International Journal of Clinical and Biomedical Research, Vol. 11, No. 3, pp. 130-134