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The Association between Coffee Consumption and Local Anaesthesia Failure

Ayah Al Hanish, Dalal Almghairbi, Mohamed Almgerbe, Amina Shimu, Hala Ali, Marwa Aqeel · AlQalam Journal of Medical and Applied Sciences;

Some patients report inadequate numbness following local anaesthesia, requiring higher-than-normal doses. Caffeine consumption has been suggested to reduce anaesthetic effectiveness. This study aimed to evaluate the eff…

Emerging Technologies in 5G Networks for IoT-Based Smart Healthcare: A Review

Fathia Adwep, Mabroka Bobreeg · AlQalam Journal of Medical and Applied Sciences;

Extensive efforts have been undertaken by governments, research institutes, and telecommunications corporations to expand the availability of fifth-generation (5G) technology. Closely integrated with the Internet of Thi…

Diabetes Mellitus in Patients with Rheumatoid Arthritis: A Systematic Review

Amani Kaawan · AlQalam Journal of Medical and Applied Sciences;

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent joint inflammation and systemic manifestations. Diabetes mellitus (DM), particularly type 2 diabetes, is a common metabolic comorbidi…

Assessment of Postoperative Pain after Cesarean Section among Libyan Women Using a Standardized Questionnaire

Mahmud Abushhewa, Omar Zaghlam, Taha Abdulrahman, Abdulati Salem, Fauzia AbdusaLam, Ashraf Naass, Surur Alhidad, Boshra Alnaier · AlQalam Journal of Medical and Applied Sciences;

This study analyzed postoperative pain experiences in 100 patients following cesarean sections (C/S), focusing on pain characteristics, medication efficacy, and functional impacts. Our findings revealed a high prevalenc…

The Contents of Fatty Acids, Phenolic Acids, Metals, and Antimicrobial Studies of Leaves and Fruits of Juniperus Phoenicea Plant

Aisha Ali, Mona Khanfar, Zuhir Akrim, Nevein Abdel-Hady, Hamad Hasan · Attahadi Medical Journal;

This study aims to determine of Fatty acids, phenolic acids, minerals, metals, and phytochemical screening in leaves and fruits of the Juniperus phoenicea plant. The extracts are also used for antimicrobial investigatio…

Cyclophosphamide-Induced Gastric Histopathological Alterations in Golden Hamsters

Maysoon Elrashdy, Rima Benomran, Esraa Farag, Mustafa Meelad, Hend Al-derbash, Mona Al-Amery, Hamed Saleh, Abeer Amer · AlQalam Journal of Medical and Applied Sciences;

Cyclophosphamide is a widely used chemotherapeutic and immunosuppressive agent, but its gastric toxicity remains poorly characterized. This study investigated dose-dependent histopathological changes in the gastric muco…

A Prevalence and Predictors of Diabetic Retinopathy among Newly Diagnosed Type 2 Diabetes Mellitus Patients in Benghazi, Libya: A Cross-Sectional Study

Ibrahim, Najah, Sanfaz, Muataz · AlQalam Journal of Medical and Applied Sciences;

Diabetic Retinopathy [DR] is a leading cause of visual impairment among adults with diabetes. Early detection is crucial, as retinal changes may be present at the time of Type 2 diabetes mellitus [T2DM] diagnosis. Limit…

Assessment of the Dermatology Life Quality Index and Its Association with Medication Adherence among Patients with Chronic Skin Conditions: A Cross-Sectional Study

Elmzughi, Rima, Alasmer, Nouralhuda, Daw, Sonia · AlQalam Journal of Medical and Applied Sciences;

Chronic inflammatory skin diseases significantly impair health-related quality of life (HRQoL), yet data on this impact and its relationship with medication adherence in Libya are scarce. To assess the QoL among Libyan…

Change in Spinopelvic Parameters Before and After Lumbar Disc Herniation Surgery

Dagistan, Emine, Kalfaoglu, Melike Elif, Dagistan, Yasar, Cicek, Caner · Advances in Modern Biomedicine;

Background: Sagittal balance depends on the interaction between lumbar alignment and spinopelvic parameters such as lumbar lordosis (LL), pelvic tilt (PT), sacral slope (SS), and pelvic incidence (PI). Although these pa…

Cortisol Signaling in Stress-Induced Pathophysiology: Molecular Mechanism and Therapeutic Implication

Gambo Mustapha, Sadiya, Nasir Hussain, Mujahid · Advances in Modern Biomedicine;

Cortisol is a glucocorticoid hormone essential for the physiological stress response. Its secretion is controlled by the hypothalamic-pituitary-adrenal (HPA) axis, which coordinates the body's adaptive behaviour to inte…

Computer-aided Discovery of Novel COX-2 Inhibitors for Anti-inflammatory Therapy Using Pharmacophore Modelling, Molecular Docking, ADMET, and Virtual Screening

Yousafzai , Usama, Najia Javed, Ali, Syed Luqman, Awais Ali, Amir Hamza · Advances in Modern Biomedicine;

Cyclooxygenase-2 (COX-2) is a central enzyme in inflammation and a validated target for anti-inflammatory drug development. However, many existing COX-2 inhibitors cause gastrointestinal and cardiovascular side effects,…

Comparative Study of Hematological-biochemical Parameters in Indigenous Sheep Reared in Semi-Desert and Mountainous Areas of Libya

Nagia Abdalsalam, Hazawy, Safia · AlQalam Journal of Medical and Applied Sciences;

This study aimed to investigate specific hematological parameters in indigenous populations. Libyan sheep are raised under two contrasting ecological zones: semi-desert and highland regions. Blood profiles provide essen…

Infection Control in Dental Settings During Management of Medically Compromised Patients: A Systematic Review

Salah Etwati · AlQalam Journal of Medical and Applied Sciences;

Medically compromised patients present unique challenges in dental care due to increased susceptibility to infections and complications. Effective infection control protocols are paramount to ensuring patient safety and…

The Mathematical Structure of the Space of Test Functions

Zohra Farnana, Thuraya Rkhayes · AlQalam Journal of Medical and Applied Sciences;

This paper aims to provide a simple and clear presentation of the mathematical structure of the space of test functions, highlighting the essential definitions, illustrative examples, and construction methods using the…

Exploring the Use of Artificial Intelligence in Developing Writing Skills: A Systematic Review

Salem Shibani · AlQalam Journal of Medical and Applied Sciences;

This systematic review aims to evaluate the capabilities of AI over the last decade in generating ideas, critiquing essays, crafting stories, and providing writing feedback, particularly for writing scholars. The study…

Gene Therapy Approaches in Hematological Malignancies: Current Strategies and Future Directions

Imran Khan Yousafzai, Aqsa Mehreen, Nadia Noreen, Nayab Ahsan, Shanzay Malik, Anza Mnahal, Sanam Rehman, Hawaida Ahmad, Khadija Tariq · Advances in Modern Biomedicine;

Hematological malignancies, such as leukemia, lymphoma, and myeloma, are cancers originating in the bone marrow and lymphatic system, marked by the uncontrolled growth of blood cells. Gene therapy offers a revolutionary…

Sleep Quality in Hemodialysis Patients According to Renal Anemia Treatment Outcomes

Basaran, Elif, Cihan Uysal · Advances in Modern Biomedicine;

Backgound: We assessed the impact of renal anemia treatment on sleep quality among hemodialysis (HD) patients. Methods: To be included in the study, patients had to have received epoetin (EPO) therapy within the past ye…

Late Management of An Atrial Septal Defect Closure Device Embolized to Left Ventricle Outflow Tract

Gunes, Yilmaz, Sincer, İsa, Erdem, Kemallettin, Özcan, Ayşenur, Akbaba, Ahmet Emre · Advances in Modern Biomedicine;

Atrial septal defect (ASD) which is among most common congenital heart disease diagnosed in adults. It is commonly managed with percutaneous closure successfully. However, percutaneous closure procedure has been associa…

Evaluation of the Relationship Between Vitamin D and Inflammation in Type 2 Diabetes and Diabetic Complications

Tuba Taslamacioglu Duman · Advances in Modern Biomedicine;

Type 2 diabetes mellitus (T2DM) and its microvascular complications are characterized by chronic inflammation, which arises as a consequence of persistent hyperglycemia and insulin resistance. In obese patients with T2D…

Formulation of a Floating Drug Delivery System for Sustained Release Delivery of Methotrexate Using Manihot Esculenta Starch

OYENIYI, Yinka James, Emmanuel C Omenazu, Rabiu TG, Andrew Onu · AlQalam Journal of Medical and Applied Sciences;

The management of rheumatoid arthritis (RA) using methotrexate (MTX) is limited by poor oral bioavailability, dose-dependent toxicity, and gastrointestinal side effects. This study aimed to formulate and evaluate a meth…

Epidemiological Landscape of Oral Tumors in Benghazi: A Retrospective Analysis

Salimah Alseefi, Sumeia Ghannay, Ali Sati, Iman Idris, Ali Elmurtadi · Attahadi Medical Journal;

The oral mucosa can be affected by non-neoplastic and neoplastic lesions, which significantly contribute to patients' mortality and morbidity, particularly with late detection. The study aimed to evaluate the demographi…

Effect of Dulaglutide on HbA1c and Vit B12, on Alloxan-Induced Diabetes in Albino Mice

Najah Balaoo, Nouh Aljarari · AlQalam Journal of Medical and Applied Sciences;

Diabetes mellitus (DM) is a metabolic disorder caused by a defect in insulin secretion, insulin action, or both; insufficient production of insulin results in prolonged elevated blood sugar levels. Insulin is initially…

T2 Dark Bands on Placental MRI as a Potential Predictor of The Severity of Post-Partum Hemorrhage in Placenta Adhesion Disorders

Nadia Rahaim, Elspeth Whitby · AlQalam Journal of Medical and Applied Sciences;

Placenta adhesion disorders (PAD) are increasingly encountered in obstetric practice due to the increase in caesarean section deliveries and placenta previa rate. If a case is confronted unexpectedly, the result is mass…

Sustainable Lipid-Based Drug Delivery: Development of Multiple Self-Emulsifying Systems for Hydrophilic Drugs Using Cashew Nut Oil

OYENIYI, Yinka James, Muhammed, Nura U · AlQalam Journal of Medical and Applied Sciences;

The oral delivery of hydrophilic drugs, such as 5-fluorouracil (5-FU), is often limited by poor permeability and rapid gastrointestinal degradation. Lipid-based self-emulsifying drug delivery systems (SEDDS) have shown…

Dose -Response Analysis of Moringa oleifera (From Jalu City, Libya) Leaf Aqueous Extracts on Mitotic Indices and Chromosomal Aberrations in Allium cepa Bioassay

El shatshat, Salem, Fawzia Al Jazwi, Salma Hamad Idris · AlQalam Journal of Medical and Applied Sciences;

This study used the Allium cepa bioassay to investigate the cytotoxicity and genotoxicity effects of water leaf extracts from Moringa trees, a plant recently introduced to Libya. Root tips were treated with different ex…